Animal-only Inteprity® now available to start at Day 18 with Maxiban® combination


A win-win-win solution that keeps birds healthy, maintains the profitability of your business, and meets consumer demands.

Inteprity is a first-in-class, animal-use only, in-feed antibiotic for the prevention of mortality caused by necrotic enteritis associated with Clostridium perfringens in broiler chickens. A win-win-win solution that meets customers’ demands without compromising bird health, helping your bottom line.

Necrotic enteritis (NE) is a serious and constant threat to the health and welfare of broiler flocks. Due to the reduction of antibiotic use and increase in coccidiosis vaccination in poultry, the incidence of necrotic enteritis is on the rise, with daily mortality rates as high as 1 percent.1,2

With a Veterinary Feed Directive (VFD), under the supervision of a veterinarian, Inteprity supports bird health and well-being, as a responsible approach to antibiotic use.

Inteprity in the field

An integrated broiler producer conducted a field trial comparing the effects of Inteprity, BMD® and Stafac® on both mortality caused by NE and performance in 21 millions broilers during the summer and fall growing periods.


Additionally, using Inteprity at 22.7 g/ton in the starter feed on days 0-21 (Chart 2) improved weight gain and adjusted feed conversion compared to feeding BMD or Stafac during the same period.


Inteprity now offers expanded feeding flexibility

Inteprity can now be implemented in the feed between Day 0 and Day 18 (fed continuously for 21 days) when fed by itself, or in combination with Maxiban®, Monteban®, Coban® or Bio-Cox® (salinomycin sodium). The Inteprity-Maxiban combination also allows Maxiban to be fed with a zero-day withdrawal when fed according to the label. By utilizing the innovation and flexibility of Inteprity, you can help keep your birds healthy while maximizing profitability.

Important Safety Information

CAUTION: Federal law restricts medicated feed containing this VFD drug to use by or on the order of a licensed veterinarian.

To assure responsible antimicrobial drug use in broiler chickens, treatment administration must begin on or before 18 days of age. When using in combination with Maxiban, Monteban, Coban and Bio-Cox, treatment and administration must begin on or before 18 days of age.

The safety of avilamycin has not been established in chickens intended for breeding purposes.

Avilamycin has not been demonstrated to be effective in broiler chickens showing clinical signs of necrotic enteritis prior to the start of medication.

The VFD expiration date must not exceed 90 days from the date of issuance. VFDs for avilamycin shall not be refilled.

Directions for Use

For the prevention of mortality caused by necrotic enteritis associated with Clostridium perfringens in broiler chickens:
Avilamycin is to be fed at 13.6 to 40.9 grams per ton of Type C medicated feed (15 to 45 ppm) as the sole ration for 21 consecutive days.

Feed to chickens that are at risk of developing, but not yet showing clinical signs of, necrotic enteritis associated with Clostridium perfringens.

1Williams, R. 2005. “Intercurrent coccidiosis and necrotic enteritis of chickens: rational, integrated disease management by maintenance of gut integrity.” Avian Pathol. 34.3: 159-180.

2Van Immerseel, F., Rood, J. et al. Jan. 2009. “Rethinking our understanding of the pathogenesis of necrotic enteritis in chickens.” Trends Microbiol. 17.1: 32-36.

3Elanco Animal Health. Data on file.

4Elanco Animal Health. Data on file.

5Elanco Animal Health. Data on file.

6Inteprity Freedom of Information Summary. (NADA 141-439)

Coban, Inteprity, Maxiban, Monteban are trademarks of Elanco or its affiliates. Other company and product names are trademarks of their respective owners.


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