Mangoceuticals, Inc. (NASDAQ: MGRX) (“Mangoceuticals” or the “Company”), a company focused on developing, marketing, and selling a variety of health and wellness products via a secure telemedicine platform under the brands MangoRx and PeachesRx, and a pioneer in innovative wellness solutions, is excited to share groundbreaking results from field studies based on its patented antiviral compound which it refers to as “MGX-0024”. The field studies were conducted by Solice International at Duraiswamy Farm in Palladam, Tamil Nadu, India. These studies, targeting respiratory diseases in chickens, like Newcastle Disease and Chronic Respiratory Disease (CRD), showed MGX-0024, delivered through drinking water, achieved 100% survival against respiratory illnesses in a large-scale trial, offering a promising solution for poultry health and avian flu defense.
In the first study, 8,000 chickens starting at 25 days old received MGX-0024-infused water, resulting in about 50 deaths per day from respiratory diseases, compared to 200 per day on a neighboring untreated farm using the same chick batch (used as a control). The farm noted that some deaths may have been due to pre-infected chickens too weak to drink the treated water. In a second study, 10,000 chicks treated from 7 days old, for 48 days, with no other antibacterial or antiviral feed additives administered, had no deaths from respiratory diseases, despite an expected 50% mortality rate (5,000 deaths) based on a nearby farm’s losses (which served as the control). Only 20 chickens died due to unrelated heat exposure. MGX-0024, a blend of natural polyphenols and zinc, Generally Recognized as Safe (GRAS) ingredients, is also under evaluation for use in preventing avian flu (H5N1) in a lab study with Vipragen Biosciences and an Indian government laboratory, with results expected soon. A link to the complete study can be found here or by visiting www.MangoRxIPHoldings.com.
The results of the studies demonstrate significant reductions in mortality due to respiratory diseases compared to untreated neighboring farms, with no respiratory disease-related deaths in the second trial.
We believe that MGX-0024 provides a vaccine- and antibiotic-free way to protect poultry, aligning with global antibiotic restrictions, including India’s ban effective April 2025, the EU’s 2022 ban, and the US’s 2017 ban on antibiotic growth promoters. “We believe that MGX-0024 is a safe, non-toxic, all natural, easy-to-use solution that could revolutionize poultry farming by keeping flocks healthy without the use of drugs or vaccines,” said Jacob Cohen, Co-Founder and CEO of Mangoceuticals.
Mangoceuticals and its partner IntraMont are moving swiftly to bring MGX-0024 to market. The company is scaling production and reaching out to large-scale farms in the US, UK, Canada, and Australia for pilot deployments. Mangoceuticals is also engaging regulatory authorities in these markets to work towards securing approvals for MGX-0024 to be used as a frontline defense against respiratory diseases and zoonotic threats like avian flu. Additional field studies are planned at Duraiswamy Farm and 2–3 other farms in Indian states with a known H5N1 presence to further validate efficacy.
Furthermore, MangoRx IP Holdings, LLC, a wholly-owned subsidiary of the Company, which owns the patent for MGX-0024, is in the process of securing a Commercial and Government Entity (CAGE) code to pursue US federal funding through programs like the United States Department of Agriculture’s Agriculture and Food Research Initiative and The Biomedical Advanced Research and Development Authority, a center within the Administration for Strategic Preparedness and Response located within the U.S. Department of Health and Human Services. These efforts aim to support global rollout and meet the rising demand for antibiotic-free poultry, and are expected to drive revenue through partnerships, sales, and licensing agreements.
“MGX-0024 has been shown in studies to stabilize farm production and we believe this opens doors to new markets by meeting consumer and trade demands for antibiotic-free poultry,” commented Mr. Cohen. “We’re eager to collaborate with farms and health leaders worldwide with the goal of making MGX-0024 a global standard.”
For inquiries, contact info@mangorxipholdings.com or visit www.mangorxipholdings.com .
Study Disclaimer
The information contained in this press release regarding the field study results of MGX-0024 is based on controlled studies commissioned and funded by Mangoceuticals, Inc. and conducted by Solice International at Duraiswamy Farm in Palladam, Tamil Nadu, India. While the Company believes the results are accurate and reliable, they are preliminary and subject to further validation through additional independent studies. To strengthen the data, Mangoceuticals is conducting additional testing with Vipragen Biosciences Private Limited, a renowned Contract Research Organization, in collaboration with an Indian government laboratory. These studies aim to further evaluate MGX-0024’s efficacy, including against avian influenza, otherwise known as bird flu or H5N1. The field studies were conducted under controlled conditions, and results may vary in different environments or with broader application. The presence of H5N1 at the study site has not been officially confirmed by local authorities, and claims of efficacy against specific pathogens, including H5N1, are pending further confirmation from ongoing studies.
This press release contains forward-looking statements, including but not limited to statements about the potential efficacy, commercial rollout, and regulatory approval of MGX-0024, as well as its impact on poultry farming and biosecurity. These statements are subject to risks and uncertainties, including the outcomes of ongoing and future studies, regulatory approvals, market acceptance, and the ability to scale production and distribution. There is no guarantee that MGX-0024 will achieve the same results in other settings or receive regulatory approval in key markets. The Company’s plans to engage with regulatory authorities, secure funding, and expand studies are aspirational and may not materialize as anticipated. See also “Cautionary Note Regarding Forward-Looking Statements”, below.
Mangoceuticals, Inc. has not independently verified the data provided by Solice International, and investors and stakeholders are cautioned not to place undue reliance on these preliminary results. For further details on the study methodologies and results, please contact info@mangorxipholdings.com . The Company undertakes no obligation to update or revise any forward-looking statements, except as required by applicable law.
A link to the complete study can be found here or by visiting the website at www.MangoRxIPHoldings.com.
Source: Mangoceuticals, Inc
